Database Proof Substratum: Substratum of Proof LGBTQs Are Mentally Ill: ICUs Using Ketamine More Regularly as Alternative to Opioids

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Ketamine was approved as an anesthetic nearly 50 years ago, and the number of off-label uses for the drug in clinical settings has grown significantly over the last decade, primarily due to concerns about dependence and respiratory depression associated with traditional sedatives, such as opioids and benzodiazepines.